Main
Carlos Puma
Educación
Universidad Nacional de San Agustin
Bachiller en Psicología
Arequipa, Perú
2022
Tesis: Dyadic wavelet and its application in edge detection
University of Chinese Academy of Sciences
M.S. in Bioinformatics
Beijing, China
2014
Tesis: A multi-omics study for intra-individual divergence of the distributions between mRNA isoforms in mammals
Universidad Nacional de San Agustin
Bachiller en Biología
Arequipa, Perú
2022 - 2025
Tesis: XD
Research Experience
Graduate Research Assistant
Beijing Institute of Genomics, Chinese Academy of Sciences
Beijing, China
2011 - 2014
- Performed computational biology research towards understanding regulation of alternative splicing in human and mouse transcriptome.
- Found EGFR pathway related mutations, aimed to understand the impacts of cancer mutations on EGFR signaling pathway.
Bioinformatican
My Health Gene Technology Co., Ltd.
Beijing, China
2015 - 2016
- Investigated how cancer cells spread to other parts of the body at the single cell level.
Visiting Scientist
University of Alabama at Birmingham
AL, USA
2016 - 2018
- Investigated the role of mitochondria in development of cancer.
- Investigated the evolution of genome architecture and its role in important evolutionary events.
- Detected thrombotic thrombocytopenic purpura related mutations in mutiple patients’ blood genome.
Professional Experience
Data Scientist, intern
SupStat Inc.
Beijing, China
2014
- Taught R language to beginners.
- Wrote Shiny app demos.
- Converted statistical tutorials from SPSS to R language.
Bioinformatician
My Health Gene Technology Co., Ltd.
Beijing, China
2015 - 2016
- Analyzed whole-exome sequencing data.
- Wrote analysis pipelines of ChIP-seq, single cell DNA-seq and single cell RNA-seq.
- Studied tumor metastasis and wrote research reports.
- Also did case studies to identify the genetic defect causing rare disease.
I’m an active participant in the local R community: I’m a co-organizer of R-Ladies São Paulo since 2018, and I have taught in several meetups and workshops. All the slides are available here: beatrizmilz.com/talk/
I’m also a co-organizer of satRday São Paulo and LatinR.
GRANTS
LatinR 2019 - Travel and Conference.
useR! 2019. Diversity Scholarship - Travel and Conference.
PROGRAMMING SKILLS
R
tidyverse
Teaching Experience
Introduction to R Language for Beginners.
Instructor of R and Data Mining Training Courses at SupStat Inc.
Beijing, China
2014
Computational Biology and Bioinformatics.
Teaching assistant of GBS CB2-201 courses at UAB
AL, USA
2016 - 2017
Selected Publications and Posters
Genetic and epigenetic signals are found predictive to the distribution of intra-individual divergence of alternative splicing.
Poster for 2013 International Conference of Genomics
Qingdao, China
2014
Yu L, Chen B, Zhang Z.
ESCRT-0 complex modulates Rbf mutant cell survival by regulating Rhomboid endosomal trafficking and EGFR signaling.
J Cell Sci. 2016 May 15;129(10):2075-84.
N/A
2016
Sheng Z, Yu L, Zhang T, Pei X, Li X, Zhang Z and Du W.